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T-cell activation is modulated by the 3D mechanical microenvironment
T cells recognize mechanical forces through a variety of cellular pathways, including mechanical triggering of both the T-cell receptor (TCR) and integrin LFA-1. Here we show that T cells can recognize forces arising from the mechanical rigidity of the microenvironment. We fabricated 3D scaffold mat...
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| Publicado no: | Biomaterials |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7307918/ https://ncbi.nlm.nih.gov/pubmed/32413594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2020.120058 |
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