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Transcriptome-wide sites of collided ribosomes reveal principles of translational pausing

Translation initiation is the major regulatory step defining the rate of protein production from an mRNA. Meanwhile, the impact of nonuniform ribosomal elongation rates is largely unknown. Using a modified ribosome profiling protocol based on footprints from two closely packed ribosomes (disomes), w...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Arpat, Alaaddin Bulak, Liechti, Angélica, De Matos, Mara, Dreos, René, Janich, Peggy, Gatfield, David
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397865/
https://ncbi.nlm.nih.gov/pubmed/32703885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.257741.119
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