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Ribosome profiling reveals the rhythmic liver translatome and circadian clock regulation by upstream open reading frames

Mammalian gene expression displays widespread circadian oscillations. Rhythmic transcription underlies the core clock mechanism, but it cannot explain numerous observations made at the level of protein rhythmicity. We have used ribosome profiling in mouse liver to measure the translation of mRNAs in...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Janich, Peggy, Arpat, Alaaddin Bulak, Castelo-Szekely, Violeta, Lopes, Maykel, Gatfield, David
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665006/
https://ncbi.nlm.nih.gov/pubmed/26486724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.195404.115
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