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Ribosome profiling reveals the rhythmic liver translatome and circadian clock regulation by upstream open reading frames

Mammalian gene expression displays widespread circadian oscillations. Rhythmic transcription underlies the core clock mechanism, but it cannot explain numerous observations made at the level of protein rhythmicity. We have used ribosome profiling in mouse liver to measure the translation of mRNAs in...

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Bibliographische Detailangaben
Veröffentlicht in:Genome Res
Hauptverfasser: Janich, Peggy, Arpat, Alaaddin Bulak, Castelo-Szekely, Violeta, Lopes, Maykel, Gatfield, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665006/
https://ncbi.nlm.nih.gov/pubmed/26486724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.195404.115
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