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Metabolic Role of PTEN in Insulin Signaling and Resistance

Phosphatase and tensin homolog (PTEN) is most prominently known for its function in tumorigenesis. However, a metabolic role of PTEN is emerging as a result of its altered expression in type 2 diabetes (T2D), which results in impaired insulin signaling and promotion of insulin resistance during the...

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Vydáno v:Cold Spring Harb Perspect Med
Hlavní autoři: Li, Yu Zhe, Di Cristofano, Antonio, Woo, Minna
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397839/
https://ncbi.nlm.nih.gov/pubmed/31964643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a036137
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