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Diminished expression of major histocompatibility complex facilitates the use of human induced pluripotent stem cells in monkey

BACKGROUND: Stem cells, including induced pluripotent stem cells (iPSCs), have tremendous potential in health care, though with several significant limitations. Each of the limitations, including immunogenicity, may block most of the therapeutic potentials. Beta2 microglobulin (B2M) and MHC II trans...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Wang, Xiaokai, Lu, Meng, Tian, Xiaoyu, Ren, Yansong, Li, Yijun, Xiang, Meng, Chen, Sifeng
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397609/
https://ncbi.nlm.nih.gov/pubmed/32746912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01847-9
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