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Diminished expression of major histocompatibility complex facilitates the use of human induced pluripotent stem cells in monkey

BACKGROUND: Stem cells, including induced pluripotent stem cells (iPSCs), have tremendous potential in health care, though with several significant limitations. Each of the limitations, including immunogenicity, may block most of the therapeutic potentials. Beta2 microglobulin (B2M) and MHC II trans...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Wang, Xiaokai, Lu, Meng, Tian, Xiaoyu, Ren, Yansong, Li, Yijun, Xiang, Meng, Chen, Sifeng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397609/
https://ncbi.nlm.nih.gov/pubmed/32746912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01847-9
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