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Histological intratumoral heterogeneity in pretreatment esophageal cancer biopsies predicts survival benefit from neoadjuvant chemotherapy: results from the UK MRC OE02 trial

Despite the use of multimodal treatment, survival of esophageal cancer (EC) patients remains poor. One proposed explanation for the relatively poor response to cytotoxic chemotherapy is intratumor heterogeneity. The aim was to establish a statistical model to objectively measure intratumor heterogen...

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書目詳細資料
發表在:Dis Esophagus
Main Authors: Davarzani, Naser, Hewitt, Lindsay C, Hale, Matthew D, Melotte, Veerle, Nankivell, Matthew, Hutchins, Gordon G A, Cunningham, David, Allum, William H, Langley, Ruth E, Jolani, Shahab, Grabsch, Heike I
格式: Artigo
語言:Inglês
出版: Oxford University Press 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397482/
https://ncbi.nlm.nih.gov/pubmed/32591823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/dote/doaa058
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