Histological intratumoral heterogeneity in pretreatment esophageal cancer biopsies predicts survival benefit from neoadjuvant chemotherapy: results from the UK MRC OE02 trial

Despite the use of multimodal treatment, survival of esophageal cancer (EC) patients remains poor. One proposed explanation for the relatively poor response to cytotoxic chemotherapy is intratumor heterogeneity. The aim was to establish a statistical model to objectively measure intratumor heterogen...

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Detalhes bibliográficos
Publicado no:Dis Esophagus
Main Authors: Davarzani, Naser, Hewitt, Lindsay C, Hale, Matthew D, Melotte, Veerle, Nankivell, Matthew, Hutchins, Gordon G A, Cunningham, David, Allum, William H, Langley, Ruth E, Jolani, Shahab, Grabsch, Heike I
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397482/
https://ncbi.nlm.nih.gov/pubmed/32591823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/dote/doaa058
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