Histological intratumoral heterogeneity in pretreatment esophageal cancer biopsies predicts survival benefit from neoadjuvant chemotherapy: results from the UK MRC OE02 trial

Despite the use of multimodal treatment, survival of esophageal cancer (EC) patients remains poor. One proposed explanation for the relatively poor response to cytotoxic chemotherapy is intratumor heterogeneity. The aim was to establish a statistical model to objectively measure intratumor heterogen...

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Dades bibliogràfiques
Publicat a:Dis Esophagus
Autors principals: Davarzani, Naser, Hewitt, Lindsay C, Hale, Matthew D, Melotte, Veerle, Nankivell, Matthew, Hutchins, Gordon G A, Cunningham, David, Allum, William H, Langley, Ruth E, Jolani, Shahab, Grabsch, Heike I
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397482/
https://ncbi.nlm.nih.gov/pubmed/32591823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/dote/doaa058
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