Structural analysis of a novel substrate-free form of the aminoglycoside 6′-N-acetyltransferase from Enterococcus faecium

Aminoglycoside acetyltransferases (AACs) catalyze the transfer of an acetyl group between acetyl-CoA and an aminoglycoside, producing CoA and an acetylated aminoglycoside. AAC(6′)-Ii enzymes target the amino group linked to the 6′ C atom in an aminoglycoside. Several structures of the AAC(6′)-Ii fro...

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Gepubliceerd in:Acta Crystallogr F Struct Biol Commun
Hoofdauteurs: Jang, Hyunseok, Kwon, Sunghark, Jeong, Chang-Sook, Lee, Chang Woo, Hwang, Jisub, Jung, Kyoung Ho, Lee, Jun Hyuck, Park, Hyun Ho
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: International Union of Crystallography 2020
Onderwerpen:
Research Communications
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397467/
https://ncbi.nlm.nih.gov/pubmed/32744248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X20009735
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