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Limitations and challenges in protein stability prediction upon genome variations: towards future applications in precision medicine

Protein stability predictions are becoming essential in medicine to develop novel immunotherapeutic agents and for drug discovery. Despite the large number of computational approaches for predicting the protein stability upon mutation, there are still critical unsolved problems: 1) the limited numbe...

詳細記述

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書誌詳細
出版年:Comput Struct Biotechnol J
主要な著者: Sanavia, Tiziana, Birolo, Giovanni, Montanucci, Ludovica, Turina, Paola, Capriotti, Emidio, Fariselli, Piero
フォーマット: Artigo
言語:Inglês
出版事項: Research Network of Computational and Structural Biotechnology 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397395/
https://ncbi.nlm.nih.gov/pubmed/32774791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.07.011
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