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PDK1/mTOR Signaling in Myeloid Cells Differentially Regulates the Early and Late Stages of Sepsis

The cecal ligation and perforation (CLP) model is the gold standard for the polymicrobial sepsis. In the CLP mice, the myeloid cells play an important role in septic shock. The phenotypes and the activation state of the macrophage and neutrophil correlate with their metabolism. In the present study,...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Du, Juan, Li, Guoli, Hua, Mingxi, Han, Junyan, Hao, Yu, Zeng, Hui, Li, Ang, Kong, Yaxian
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397376/
https://ncbi.nlm.nih.gov/pubmed/32774145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/5437175
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