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The GTPase-activating protein p120RasGAP has an evolutionarily conserved “FLVR-unique” SH2 domain
The Src homology 2 (SH2) domain has a highly conserved architecture that recognizes linear phosphotyrosine motifs and is present in a wide range of signaling pathways across different evolutionary taxa. A hallmark of SH2 domains is the arginine residue in the conserved FLVR motif that forms a direct...
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| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7397115/ https://ncbi.nlm.nih.gov/pubmed/32540970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013976 |
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