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SpCas9- and LbCas12a-Mediated DNA Editing Produce Different Gene Knockout Outcomes in Zebrafish Embryos

CRISPR/Cas (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR associated protein) genome editing is a powerful technology widely used in current genetic research. In the most simple and straightforward way it can be applied for a gene knockout resulting from repair errors, induced by...

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Bibliografski detalji
Izdano u:Genes (Basel)
Glavni autori: Meshalkina, Darya A., Glushchenko, Aleksei S., Kysil, Elana V., Mizgirev, Igor V., Frolov, Andrej
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397077/
https://ncbi.nlm.nih.gov/pubmed/32635161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11070740
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