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Bioorthogonal Click Chemistries Enable Simultaneous Spatial Patterning of Multiple Proteins to Probe Synergistic Protein Effects on Fibroblast Function
Three biorthogonal click reactions, a photoinitiated thiol-yne reaction, an azide-alkyne cycloaddition, and a methyltetrazine-transcyclooctene Diels Alder, were used to independently control the presentation of several bioactive proteins to valvular interstitial cells (VICs) in hydrogel scaffolds. T...
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| Publicado no: | Biomaterials |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7396286/ https://ncbi.nlm.nih.gov/pubmed/32574845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2020.120205 |
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