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Clinical Efficacy Evaluation of Sirolimus in Congenital Hyperinsulinism

BACKGROUND: Congenital hyperinsulinism (CHI) is a rare and life-threatening genetic disorder. Sirolimus as a mammalian target of rapamycin inhibitor may be helpful in patients with CHI who do not respond well to other treatments including diazoxide and octreotide. However, the safety and efficacy of...

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Detalhes bibliográficos
Publicado no:Int J Endocrinol
Main Authors: Hashemian, Somayyeh, Jafarzadeh Esfehani, Reza, Karimdadi, Siroos, Vakili, Rahim, Zamanfar, Daniel, Sahebkar, Amirhossein
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7396056/
https://ncbi.nlm.nih.gov/pubmed/32774365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7250406
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