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Dynamical gene regulatory networks are tuned by transcriptional autoregulation with microRNA feedback

Concepts from dynamical systems theory, including multi-stability, oscillations, robustness and stochasticity, are critical for understanding gene regulation during cell fate decisions, inflammation and stem cell heterogeneity. However, the prevalence of the structures within gene networks that driv...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Minchington, Thomas G., Griffiths-Jones, Sam, Papalopulu, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395740/
https://ncbi.nlm.nih.gov/pubmed/32737375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69791-5
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