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Dynamical gene regulatory networks are tuned by transcriptional autoregulation with microRNA feedback

Concepts from dynamical systems theory, including multi-stability, oscillations, robustness and stochasticity, are critical for understanding gene regulation during cell fate decisions, inflammation and stem cell heterogeneity. However, the prevalence of the structures within gene networks that driv...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Minchington, Thomas G., Griffiths-Jones, Sam, Papalopulu, Nancy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395740/
https://ncbi.nlm.nih.gov/pubmed/32737375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69791-5
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