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Population Pharmacokinetics of Tacrolimus in Transplant Recipients: What Did We Learn About Sources of Interindividual Variabilities?

Tacrolimus, a calcineurin inhibitor, is a common immunosuppressant prescribed after organ transplantation and has notable inter- and intrapatient pharmacokinetic variability. The sources of variability have been investigated using population pharmacokinetic modeling over the last 2 decades. This art...

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Vydáno v:J Clin Pharmacol
Hlavní autoři: Campagne, Olivia, Mager, Donald E., Tornatore, Kathleen M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395655/
https://ncbi.nlm.nih.gov/pubmed/30371942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1325
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