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Chimeric hemagglutinin vaccine elicits broadly protective CD4 and CD8 T cell responses against multiple influenza strains and subtypes

Vaccination has been used to control the spread of seasonal flu; however, the virus continues to evolve and escape from host immune response through mutation and increasing glycosylation. Efforts have been directed toward development of a universal vaccine with broadly protective activity against mu...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Liao, Hsin-Yu, Wang, Shih-Chi, Ko, Yi-An, Lin, Kuo-I, Ma, Che, Cheng, Ting-Jen Rachel, Wong, Chi-Huey
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395492/
https://ncbi.nlm.nih.gov/pubmed/32669430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004783117
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