Identification of the initial nucleocapsid recognition element in the HIV-1 RNA packaging signal

Selective packaging of the HIV-1 genome during virus assembly is mediated by interactions between the dimeric 5ʹ-leader of the unspliced viral RNA and the nucleocapsid (NC) domains of a small number of assembling viral Gag polyproteins. Here, we show that the dimeric 5′-leader contains more than two...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Ding, Pengfei, Kharytonchyk, Siarhei, Waller, Alexis, Mbaekwe, Ugonna, Basappa, Sapna, Kuo, Nansen, Frank, Heather M., Quasney, Christina, Kidane, Aaron, Swanson, Canessa, Van, Verna, Sarkar, Mitali, Cannistraci, Emily, Chaudhary, Ridhi, Flores, Hana, Telesnitsky, Alice, Summers, Michael F.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2020
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395439/
https://ncbi.nlm.nih.gov/pubmed/32647061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2008519117
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