Regulation of stem cell function and neuronal differentiation by HERV-K via mTOR pathway

Stem cells are capable of unlimited proliferation but can be induced to form brain cells. Factors that specifically regulate human development are poorly understood. We found that human stem cells expressed high levels of the envelope protein of an endogenized human-specific retrovirus (HERV-K, HML-...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wang, Tongguang, Medynets, Marie, Johnson, Kory R., Doucet-O’Hare, Tara T., DiSanza, Brianna, Li, Wenxue, Xu, Yadi, Bagnell, Anna, Tyagi, Richa, Sampson, Kevon, Malik, Nasir, Steiner, Joseph, Hadegan, Alina, Kowalak, Jeffrey, O'Malley, James, Maric, Dragan, Nath, Avindra
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395438/
https://ncbi.nlm.nih.gov/pubmed/32669437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2002427117
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