Erythrocyte-driven immunization via biomimicry of their natural antigen-presenting function

Erythrocytes naturally capture certain bacterial pathogens in circulation, kill them through oxidative stress, and present them to the antigen-presenting cells (APCs) in the spleen. By leveraging this innate immune function of erythrocytes, we developed erythrocyte-driven immune targeting (EDIT), wh...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Ukidve, Anvay, Zhao, Zongmin, Fehnel, Alexandra, Krishnan, Vinu, Pan, Daniel C., Gao, Yongsheng, Mandal, Abhirup, Muzykantov, Vladimir, Mitragotri, Samir
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395435/
https://ncbi.nlm.nih.gov/pubmed/32665441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2002880117
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