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Xanthohumol Isolated from Humulus lupulus Inhibits Menadione-Induced DNA Damage through Induction of Quinone Reductase

The female parts of hops (Humulus lupulus L.) show estrogenic effects as well as cancer chemopreventive potential. We analyzed the chemopreventive mechanism of hops by studying its antioxidative activities and its effect on the detoxification of a potentially toxic quinone (menadione). The detoxific...

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Detalhes bibliográficos
Publicado no:Chem Res Toxicol
Main Authors: Dietz, Birgit M., Kang, Young-Hwa, Liu, Guowen, Eggler, Aimee L., Yao, Ping, Chadwick, Lucas R., Pauli, Guido F., Farnsworth, Norman R., Mesecar, Andrew D., van Breemen, Richard B., Bolton, Judy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395304/
https://ncbi.nlm.nih.gov/pubmed/16097803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx050058x
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