Ablation of aryl hydrocarbon receptor promotes angiotensin II-induced cardiac fibrosis through enhanced c-Jun/HIF-1α signaling

Aryl hydrocarbon receptor (AHR) is a transcription factor that binds to DNA as a heterodimer with the AHR nuclear translocator (ARNT) after interaction with ligands, such as polycyclic and halogenated aromatic hydrocarbons and other xenobiotics. The endogenous ligands and functions of AHR have been...

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Gepubliceerd in:Arch Toxicol
Hoofdauteurs: Ichihara, Sahoko, Li, Ping, Mise, Nathan, Suzuki, Yuka, Izuoka, Kiyora, Nakajima, Tamie, Gonzalez, Frank, Ichihara, Gaku
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395242/
https://ncbi.nlm.nih.gov/pubmed/31016362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-019-02446-1
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