Evolutionarily Conserved Roles for Apontic in Induction and Subsequent Decline of Cyclin E Expression

Cyclin E is a key factor for S phase entry, and deregulation of Cyclin E results in developmental defects and tumors. Therefore, proper cycling of Cyclin E is crucial for normal growth. Here we found that transcription factors Apontic (Apt) and E2f1 cooperate to induce cyclin E in Drosophila. Functi...

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Vydáno v:iScience
Hlavní autoři: Wang, Xian-Feng, Liu, Jin-Xiao, Ma, Zhi-Yuan, Shen, Yang, Zhang, Hao-Ran, Zhou, Zi-Zhang, Suzuki, Emiko, Liu, Qing-Xin, Hirose, Susumu
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394757/
https://ncbi.nlm.nih.gov/pubmed/32736066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101369
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