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Apontic directly activates hedgehog and cyclin E for proper organ growth and patterning
Hedgehog (Hh) signaling pathway and Cyclin E are key players in cell proliferation and organ development. Hyperactivation of hh and cyclin E has been linked to several types of cancer. However, coordination of the expression of hh and cyclin E was not well understood. Here we show that an evolutiona...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5622130/ https://ncbi.nlm.nih.gov/pubmed/28963499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12766-w |
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