A conserved coccidian gene is involved in Toxoplasma sensitivity to the anti-apicomplexan compound, tartrolon E

New treatments for the diseases caused by apicomplexans are needed. Recently, we determined that tartrolon E (trtE), a secondary metabolite derived from a shipworm symbiotic bacterium, has broad-spectrum anti-apicomplexan parasite activity. TrtE inhibits apicomplexans at nM concentrations in vitro,...

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Publié dans:Int J Parasitol Drugs Drug Resist
Auteurs principaux: Bowden, Gregory D., Reis, Patricia M., Rogers, Maxwell B., Bone Relat, Rachel M., Brayton, Kelly A., Wilson, Sarah K., Di Genova, Bruno Martorelli, Knoll, Laura J., Nepveux V, Felix J., Tai, Albert K., Ramadhar, Timothy R., Clardy, Jon, O'Connor, Roberta M.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394737/
https://ncbi.nlm.nih.gov/pubmed/32738587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2020.07.003
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