A conserved coccidian gene is involved in Toxoplasma sensitivity to the anti-apicomplexan compound, tartrolon E

New treatments for the diseases caused by apicomplexans are needed. Recently, we determined that tartrolon E (trtE), a secondary metabolite derived from a shipworm symbiotic bacterium, has broad-spectrum anti-apicomplexan parasite activity. TrtE inhibits apicomplexans at nM concentrations in vitro,...

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Veröffentlicht in:Int J Parasitol Drugs Drug Resist
Hauptverfasser: Bowden, Gregory D., Reis, Patricia M., Rogers, Maxwell B., Bone Relat, Rachel M., Brayton, Kelly A., Wilson, Sarah K., Di Genova, Bruno Martorelli, Knoll, Laura J., Nepveux V, Felix J., Tai, Albert K., Ramadhar, Timothy R., Clardy, Jon, O'Connor, Roberta M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394737/
https://ncbi.nlm.nih.gov/pubmed/32738587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2020.07.003
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