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MISTIC: A prediction tool to reveal disease-relevant deleterious missense variants

The diffusion of next-generation sequencing technologies has revolutionized research and diagnosis in the field of rare Mendelian disorders, notably via whole-exome sequencing (WES). However, one of the main issues hampering achievement of a diagnosis via WES analyses is the extended list of variant...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chennen, Kirsley, Weber, Thomas, Lornage, Xavière, Kress, Arnaud, Böhm, Johann, Thompson, Julie, Laporte, Jocelyn, Poch, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394404/
https://ncbi.nlm.nih.gov/pubmed/32735577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0236962
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