Inhibition of Sonic Hedgehog Signaling Suppresses Glioma Stem-Like Cells Likely Through Inducing Autophagic Cell Death

Glioblastoma (GBM) often recurs after radio- and chemotherapies leading to poor prognosis. Glioma stem-like cells (GSCs) contribute to drug resistance and recurrence. Thus, understanding cellular mechanism underlying the growth of GSCs is critical for the treatment of GBM. Here GSCs were isolated fr...

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Detalles Bibliográficos
Publicado en:Front Oncol
Main Authors: Hung, Hui-Chi, Liu, Chan-Chuan, Chuang, Jian-Ying, Su, Chun-Lin, Gean, Po-Wu
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7393230/
https://ncbi.nlm.nih.gov/pubmed/32793494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01233
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