Cyclic AMP in human preterm infant blood is associated with increased TLR-mediated production of acute-phase and anti-inflammatory cytokines in vitro

BACKGROUND: Preterm infants are at high risk of infection and have distinct pathogen recognition responses. Suggested mechanisms include soluble mediators that enhance cellular levels of cAMP. OBJECTIVE: To assess the relationship between blood cAMP concentrations and TLR-mediated cytokine productio...

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Published in:Pediatr Res
Main Authors: Strunk, Tobias, van Haren, Simon D., Hibbert, Julie, Pettengill, Matthew, Ozonoff, Al, Jans, Jop, Schüller, Simone S., Burgner, David, Levy, Ofer, Currie, Andrew J.
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7392158/
https://ncbi.nlm.nih.gov/pubmed/31578034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41390-019-0586-2
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