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M1 muscarinic acetylcholine receptor dysfunction in moderate Alzheimer’s disease pathology

Aggregation of amyloid beta and loss of cholinergic innervation in the brain are predominant components of Alzheimer’s disease pathology and likely underlie cognitive impairment. Acetylcholinesterase inhibitors are one of the few treatment options for Alzheimer’s disease, where levels of available a...

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Detalhes bibliográficos
Publicado no:Brain Commun
Main Authors: Yi, Jee Hyun, Whitcomb, Daniel J, Park, Se Jin, Martinez-Perez, Celia, Barbati, Saviana A, Mitchell, Scott J, Cho, Kwangwook
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7391992/
https://ncbi.nlm.nih.gov/pubmed/32766549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/braincomms/fcaa058
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