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Glycerol-3-phosphate Acyltransferase1 Is a Model-Agnostic Node in Nonalcoholic Fatty Liver Disease: Implications for Drug Development and Precision Medicine

[Image: see text] Left untreated nonalcoholic fatty liver disease (NAFLD) can progress to nonalcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and hepatocellular carcinoma. The observed failure of clinical trials in NASH may suggest that current model systems do not fully recapitulate human dis...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Liao, Kimberly, Pellicano, Anthony J., Jiang, Kai, Prakash, Natalia, Li, Jingsong, Bhutkar, Shraddha, Hu, Zhijian, Ali, Quaisar, Goldberg, Itzhak D., Narayan, Prakash
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7391940/
https://ncbi.nlm.nih.gov/pubmed/32743224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c02350
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