Glycerol-3-phosphate Acyltransferase1 Is a Model-Agnostic Node in Nonalcoholic Fatty Liver Disease: Implications for Drug Development and Precision Medicine

[Image: see text] Left untreated nonalcoholic fatty liver disease (NAFLD) can progress to nonalcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and hepatocellular carcinoma. The observed failure of clinical trials in NASH may suggest that current model systems do not fully recapitulate human dis...

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Veröffentlicht in:ACS Omega
Hauptverfasser: Liao, Kimberly, Pellicano, Anthony J., Jiang, Kai, Prakash, Natalia, Li, Jingsong, Bhutkar, Shraddha, Hu, Zhijian, Ali, Quaisar, Goldberg, Itzhak D., Narayan, Prakash
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2020
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7391940/
https://ncbi.nlm.nih.gov/pubmed/32743224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c02350
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