Altered mechanisms of genital development identified through integration of DNA methylation and genomic measures in hypospadias

Hypospadias is a common birth defect where the urethral opening forms on the ventral side of the penis. We performed integrative methylomic, genomic, and transcriptomic analyses to characterize sites of DNA methylation that influence genital development. In case–control and case-only epigenome-wide...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Richard, Melissa A., Sok, Pagna, Canon, Stephen, Nembhard, Wendy N., Brown, Austin L., Peckham-Gregory, Erin C., Ton, Minh, Ehli, Erik A., Kallsen, Noah A., Peyton, Shanna A., Davies, Gareth E., Patel, Ashay, Zamilpa, Ismael, Hobbs, Charlotte A., Scheurer, Michael E., Lupo, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7391634/
https://ncbi.nlm.nih.gov/pubmed/32728162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69725-1
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