Systematic Characterization of Recurrent Genomic Alterations in Cyclin-Dependent Kinases Reveals Potential Therapeutic Strategies for Cancer Treatment

Recurrent copy-number alterations, mutations, and transcript fusions of the genes encoding CDKs/cyclins are characterized in >10,000 tumors. Genomic alterations of CDKs/cyclins are dominantly driven by copy number aberrations. In contrast to cell-cycle-related CDKs/cyclins, which are globally amp...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Shan, Weiwei, Yuan, Jiao, Hu, Zhongyi, Jiang, Junjie, Wang, Yueying, Loo, Nicki, Fan, Lingling, Tang, Zhaoqing, Zhang, Tianli, Xu, Mu, Pan, Yutian, Lu, Jiaqi, Long, Meixiao, Tanyi, Janos L., Montone, Kathleen T., Fan, Yi, Hu, Xiaowen, Zhang, Youyou, Zhang, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7391471/
https://ncbi.nlm.nih.gov/pubmed/32668240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107884
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados