Genomic characterization of genes encoding histone acetylation modulator proteins identifies therapeutic targets for cancer treatment

A growing emphasis in anticancer drug discovery efforts has been on targeting histone acetylation modulators. Here we comprehensively analyze the genomic alterations of the genes encoding histone acetylation modulator proteins (HAMPs) in the Cancer Genome Atlas cohort and observe that HAMPs have a h...

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Publicado no:Nat Commun
Main Authors: Hu, Zhongyi, Zhou, Junzhi, Jiang, Junjie, Yuan, Jiao, Zhang, Youyou, Wei, Xuepeng, Loo, Nicki, Wang, Yueying, Pan, Yutian, Zhang, Tianli, Zhong, Xiaomin, Long, Meixiao, Montone, Kathleen T., Tanyi, Janos L., Fan, Yi, Wang, Tian-Li, Shih, Ie-Ming, Hu, Xiaowen, Zhang, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374416/
https://ncbi.nlm.nih.gov/pubmed/30760718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08554-x
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