OvCa-Chip microsystem recreates vascular endothelium–mediated platelet extravasation in ovarian cancer

In ovarian cancer, platelet extravasation into the tumor and resulting metastasis is thought to be regulated mostly by the vascular endothelium. Because it is difficult to dissect complex underlying events in murine models, organ-on-a-chip methodology is applied to model vascular and platelet functi...

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Опубликовано в: :Blood Adv
Главные авторы: Saha, Biswajit, Mathur, Tanmay, Handley, Katelyn F., Hu, Wei, Afshar-Kharghan, Vahid, Sood, Anil K., Jain, Abhishek
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2020
Предметы:
Thrombosis and Hemostasis
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7391144/
https://ncbi.nlm.nih.gov/pubmed/32717032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001632
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