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OvCa-Chip microsystem recreates vascular endothelium–mediated platelet extravasation in ovarian cancer

In ovarian cancer, platelet extravasation into the tumor and resulting metastasis is thought to be regulated mostly by the vascular endothelium. Because it is difficult to dissect complex underlying events in murine models, organ-on-a-chip methodology is applied to model vascular and platelet functi...

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Bibliographische Detailangaben
Veröffentlicht in:Blood Adv
Hauptverfasser: Saha, Biswajit, Mathur, Tanmay, Handley, Katelyn F., Hu, Wei, Afshar-Kharghan, Vahid, Sood, Anil K., Jain, Abhishek
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7391144/
https://ncbi.nlm.nih.gov/pubmed/32717032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001632
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