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von Willebrand factor is a cofactor in complement regulation
Several complement proteins interact with hemostatic factors. We discovered that von Willebrand factor (VWF) acts as a cofactor for factor I–mediated cleavage of complement C3b, thereby shutting down complement activation. The complement regulatory function of VWF multimers depends on their size. Sm...
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| Vydáno v: | Blood |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Hematology
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4319234/ https://ncbi.nlm.nih.gov/pubmed/25395424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-06-585430 |
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