Extra copies of MYC, BCL2, and BCL6 and outcome in patients with diffuse large B-cell lymphoma

High-grade B-cell lymphoma (HGBL) with translocations involving MYC and BCL2 or BCL6 comprises ∼10% of cases of diffuse large B-cell lymphoma (DLBCL) and carries a poor prognosis. The incidence, prognosis, and optimal therapy for DLBCL harboring extra copies of the genes MYC, BCL2, and BCL6, rather...

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Опубликовано в: :Blood Adv
Главные авторы: Sermer, David, Bobillo, Sabela, Dogan, Ahmet, Zhang, Yanming, Seshan, Venkatraman, Lavery, Jessica A., Batlevi, Connie, Caron, Philip, Hamilton, Audrey, Hamlin, Paul, Horwitz, Steven, Joffe, Erel, Kumar, Anita, Matasar, Matthew, Noy, Ariela, Owens, Colette, Moskowitz, Alison, Palomba, M. Lia, Straus, David, von Keudell, Gottfried, Rodriguez-Rivera, Ildefonso, Falchi, Lorenzo, Zelenetz, Andrew, Yahalom, Joachim, Younes, Anas
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2020
Предметы:
Clinical Trials and Observations
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7391142/
https://ncbi.nlm.nih.gov/pubmed/32722781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001551
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