Prophylaxis with intrathecal or high-dose methotrexate in diffuse large B-cell lymphoma and high risk of CNS relapse

Although methotrexate (MTX) is the most widely used therapy for central nervous system (CNS) prophylaxis in patients with diffuse large B-cell lymphoma (DLBCL), the optimal regimen remains unclear. We examined the efficacy of different prophylactic regimens in 585 patients with newly diagnosed DLBCL...

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Foilsithe in:Blood Cancer J
Main Authors: Bobillo, Sabela, Joffe, Erel, Sermer, David, Mondello, Patrizia, Ghione, Paola, Caron, Philip C., Hamilton, Audrey, Hamlin, Paul A., Horwitz, Steven M., Kumar, Anita, Matasar, Matthew J., Batlevi, Connie L., Moskowitz, Alison, Noy, Ariela, Owens, Collette N., Palomba, M. Lia, Straus, David, von Keudell, Gottfried, Dogan, Ahmet, Zelenetz, Andrew D., Seshan, Venkatraman E., Younes, Anas
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2021
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209097/
https://ncbi.nlm.nih.gov/pubmed/34135307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-021-00506-3
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