Prophylaxis with intrathecal or high-dose methotrexate in diffuse large B-cell lymphoma and high risk of CNS relapse

Although methotrexate (MTX) is the most widely used therapy for central nervous system (CNS) prophylaxis in patients with diffuse large B-cell lymphoma (DLBCL), the optimal regimen remains unclear. We examined the efficacy of different prophylactic regimens in 585 patients with newly diagnosed DLBCL...

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Publicat a:Blood Cancer J
Autors principals: Bobillo, Sabela, Joffe, Erel, Sermer, David, Mondello, Patrizia, Ghione, Paola, Caron, Philip C., Hamilton, Audrey, Hamlin, Paul A., Horwitz, Steven M., Kumar, Anita, Matasar, Matthew J., Batlevi, Connie L., Moskowitz, Alison, Noy, Ariela, Owens, Collette N., Palomba, M. Lia, Straus, David, von Keudell, Gottfried, Dogan, Ahmet, Zelenetz, Andrew D., Seshan, Venkatraman E., Younes, Anas
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209097/
https://ncbi.nlm.nih.gov/pubmed/34135307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-021-00506-3
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