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Tmc proteins are essential for zebrafish hearing where Tmc1 is not obligatory

Perception of sound is initiated by mechanically gated ion channels at the tips of stereocilia. Mature mammalian auditory hair cells require transmembrane channel-like 1 (TMC1) for mechanotransduction, and mutations of the cognate genetic sequences result in dominant or recessive heritable deafness...

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Bibliografske podrobnosti
izdano v:Hum Mol Genet
Main Authors: Chen, Zongwei, Zhu, Shaoyuan, Kindig, Kayla, Wang, Shengxuan, Chou, Shih-Wei, Davis, Robin Woods, Dercoli, Michael R, Weaver, Hannah, Stepanyan, Ruben, McDermott, Brian M
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390940/
https://ncbi.nlm.nih.gov/pubmed/32167554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa045
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