Tmc proteins are essential for zebrafish hearing where Tmc1 is not obligatory

Perception of sound is initiated by mechanically gated ion channels at the tips of stereocilia. Mature mammalian auditory hair cells require transmembrane channel-like 1 (TMC1) for mechanotransduction, and mutations of the cognate genetic sequences result in dominant or recessive heritable deafness...

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Publicat a:Hum Mol Genet
Autors principals: Chen, Zongwei, Zhu, Shaoyuan, Kindig, Kayla, Wang, Shengxuan, Chou, Shih-Wei, Davis, Robin Woods, Dercoli, Michael R, Weaver, Hannah, Stepanyan, Ruben, McDermott, Brian M
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
General Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390940/
https://ncbi.nlm.nih.gov/pubmed/32167554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa045
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