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Effects of Heat Shock Protein 90 Inhibition In the Lungs

Inhibition of Hsp90 is associated with anti-inflammatory effects. We employed human lung microvascular endothelial cells to investigate the effects of the Hsp90 inhibitors 17-AAG, AUY-922 and 17-DMAG in the unfolded protein response (UPR) and viability of lung cells. Our observations indicate that m...

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Detalhes bibliográficos
Publicado no:Med Drug Discov
Main Authors: Uddin, Mohammad A., Kubra, Khadeja-Tul, Sonju, Jafrin Jobayer, Akhter, Mohammad S., Seetharama, Jois, Barabutis, Nektarios
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390472/
https://ncbi.nlm.nih.gov/pubmed/32728665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.medidd.2020.100046
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