Galunisertib enhances chimeric antigen receptor-modified T cell function

Chimeric antigen receptor (CAR) T cell therapy still faces the challenge of immunosuppression when treating solid tumors. TGF-β is one of the critical factors in the tumor microenvironment to help tumors escape surveillance by the immune system. Here we tried using the combination of a small molecul...

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Gepubliceerd in:Eur J Histochem
Hoofdauteurs: Wang, Zhixiong, Liu, Qian, Risu, Na, Fu, Jiayu, Zou, Yan, Tang, Jiaxing, Li, Long, Liu, Hui, Zhou, Guomin, Zhu, Xuekai
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: PAGEPress Publications, Pavia, Italy 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7388644/
https://ncbi.nlm.nih.gov/pubmed/32705856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/ejh.2020.3122
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