BAY 60-6583 Enhances the Antitumor Function of Chimeric Antigen Receptor-Modified T Cells Independent of the Adenosine A2b Receptor

Chimeric antigen receptor (CAR) T cells are powerful in eradicating hematological malignancies, but their efficacy is limited in treating solid tumors. One of the barriers is the immunosuppressive response induced by immunomodulatory signaling pathways. Pharmacological targeting of these immunosuppr...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Tang, Jiaxing, Zou, Yan, Li, Long, Lu, Fengping, Xu, Hongtao, Ren, Pengxuan, Bai, Fang, Niedermann, Gabriele, Zhu, Xuekai
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7994267/
https://ncbi.nlm.nih.gov/pubmed/33776765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.619800
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