Efficient detection of differentially methylated regions in the genome of patients with thoracic aortic dissection and association with MMP2 hypermethylation

DNA methylation is known to regulate the expression of numerous genes but its role in the pathogenesis of thoracic aortic dissection (TAD) has remained largely elusive. In the present study, the DNA methylome of patients with TAD was analyzed using a methylation microarray and bisulfite pyrosequenci...

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Vydáno v:Exp Ther Med
Hlavní autoři: Li, Ni, Lin, Hangjuan, Zhou, Hua, Zheng, Dawei, Xu, Guodong, Shi, Huoshun, Zhu, Xiuying, Gao, Jianqing, Shao, Guofeng, Sun, Lebo
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7388572/
https://ncbi.nlm.nih.gov/pubmed/32765660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.8753
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