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Efficient detection of differentially methylated regions in the genome of patients with thoracic aortic dissection and association with MMP2 hypermethylation

DNA methylation is known to regulate the expression of numerous genes but its role in the pathogenesis of thoracic aortic dissection (TAD) has remained largely elusive. In the present study, the DNA methylome of patients with TAD was analyzed using a methylation microarray and bisulfite pyrosequenci...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Li, Ni, Lin, Hangjuan, Zhou, Hua, Zheng, Dawei, Xu, Guodong, Shi, Huoshun, Zhu, Xiuying, Gao, Jianqing, Shao, Guofeng, Sun, Lebo
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7388572/
https://ncbi.nlm.nih.gov/pubmed/32765660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.8753
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