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Efficient detection of differentially methylated regions in the genome of patients with thoracic aortic dissection and association with MMP2 hypermethylation

DNA methylation is known to regulate the expression of numerous genes but its role in the pathogenesis of thoracic aortic dissection (TAD) has remained largely elusive. In the present study, the DNA methylome of patients with TAD was analyzed using a methylation microarray and bisulfite pyrosequenci...

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Detaylı Bibliyografya
Yayımlandı:Exp Ther Med
Asıl Yazarlar: Li, Ni, Lin, Hangjuan, Zhou, Hua, Zheng, Dawei, Xu, Guodong, Shi, Huoshun, Zhu, Xiuying, Gao, Jianqing, Shao, Guofeng, Sun, Lebo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: D.A. Spandidos 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7388572/
https://ncbi.nlm.nih.gov/pubmed/32765660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.8753
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