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Acute lengthening of progenitor mitosis influences progeny fate during cortical development in vivo

Prenatal microcephaly is posited to arise from aberrant mitosis of neural progenitors, which disrupts both neuronal production and survival. Although microcephaly has both a genetic and environmental etiology, the mechanisms by which dysregulation of mitosis causes microcephaly are poorly understood...

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Bibliographische Detailangaben
Veröffentlicht in:Dev Neurosci
Hauptverfasser: Mitchell-Dick, Aaron, Chalem, Andrea, Pilaz, Louis-Jan, Silver, Debra L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7388066/
https://ncbi.nlm.nih.gov/pubmed/32541147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000507113
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